Zelenska K. The mechanisms of formation and system of psychoprophylaxis of suicidal behavior in young patients with depression

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U005888

Thesis Registration Form

0415U005888.pdf

Applicant for

Specialization

  • 14.01.16 - Психіатрія

28-10-2015

Specialized Academic Board

Д 64.566.01

State institution "Institute of Neurology, Psychiatry and Narcology, National Academy of Medical Sciences of Ukraine"

Essay

The work covers the study of the formation of suicidal behavior in young adults with depressive disorders and developing of pathogenetic based system of its prevention. There were clinical and psychopathological signs of depressive disorders in young patients analyzed. Anxiety, asthenia, asthenic-apathetic and melancholy variants of depressive disorders in young patients with suicidal behavior were highlighted. In this study there were the markers of suicide risk for young patients with depressive disorders determined: high suicide risk, low death self-consciousness, high anhedonia level, clinical manifestations of anxiety and depression by The Hospital Anxiety and Depression scale, severe anxiety and depression by The Hamilton Anxiety Rating Scale, major depressive episode by the Montgomery-Asberg Depression Rating Scale. It has been proved that in observed young patients with depressive disorders with suicide behavior increased concentrations of serotonin, cortisol, noradrenaline and decreased levels of adrenaline and melatonine in plasma were observed. These changes were determined as neurohormonal background for depletion of adaptation resource in stresssituations. A model of suicidal behavior in young adults with depressive disorders was designed.

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