Makarchuk A. Correction of involutive face skin changes in patients with associated malassezia infection

The object of study - involutive skin changes in patients with concomitant malassezia infection. The purpose of research - increase the effectiveness of therapy of involutive skin changes in patients with malassezia infection through the development of the phased complex preparatory and basic form of therapy based on patient age, clinical and morphological characteristics of the surface condition and structure of the skin. Methods: clinical, histologic, electron microscopic, morphometric, clinical and instrumental, mathemathical. A complex differential therapy for patients with involutive face skin changes complicated by malassezia has been developed in accordance with the divided groups. The therapy allowed to accelerate the process of rehabilitation of patients after surgery and to achieve a better aesthetic result. The developed technique of differentiated treatment contributed to sufficiently high efficacy in patients with involutive changes of the skin and related malassezia (itraconazole, thiotriazoline, ursofalk), as well as externally with bifonazole lotion. The findings put into practice the work of Municipal Institution "Zaporizhzhia Regional Skin and Venereal Diseases Clinical Dispensary" of Zaporizhzhia Regional Council, Municipal Institution "Rivne Regional Skin and Venereal Diseases Dispensary" of Rivne Regional Council, Municipal Institution of Healthcare Regional Clinical Skin and Venereal Diseases Dispensary number 1 (Kharkiv), Municipal Institution "Regional Skin and Venereal Diseases dispensary" (Dnipropetrovsk), Municipal Institution of Healthcare "Kharkiv City Cosmetological Hospital", Poltava Regional Clinical Skin and Venereal Diseases Dispensary, Limited liability company "Clinic of plastic surgery and cosmetology "Artmedica", Ukrainian Institute of Plastic Surgery and Aesthetic Medicine "Virtus" (Odesa), Medical Center "MediCell", as well as in the educational process of the department of dermatovenerology and cosmetology with the course of dermatovenerology and aesthetic medicine DPE of Zaporizhzhia State Medical University, the department of skin and venereal diseases and Department of histology of State Institution "Dnipropetrovsk medical academy of Ministry of Healthcare of Ukraine", the department of phthisiatry with skin and venereal diseases of the Higher State Educational Institution of Ukraine "Ukrainian medical stomatological academy", at the department of dermatovenerology of the National Medical Academy of Postgraduate Education named after P.L. Shupyk. Area of usage - Dermatovenerology.