Rusalkina S. The differentiated approach to preventive maintenance incompetent pregnancy at women with metabolic syndrome.

Scientific work is devoted frequency decrease incompetent pregnancy and perinatal pathology at women with metabolic syndrome on a basis studying at them clinical-functional, biochemical, immunological, endocrinological and microbiological features, and also working out the differentiated approach to carrying out of diagnostic and treatment-and-prophylactic actions. Negative influence of metabolic syndrome on clinical current of pregnancy and labours that leads to high level obstetrical and perinatal complications, especially incompetent pregnancy in 1 trimester of pregnancy is scientifically proved. Studying the basic features of formation and a functional condition fetoplacental complex at women with a metabolic syndrome which consist in early development (from 20 weeks of pregnancy) haemodynamic (blood-groove strengthening in an artery of an umbilical cord and uterine arteries against blood-groove decrease in a middle-brain artery of fetus) and endocrinological infringements (maintenance decrease estriole, a progesterone, horionale gonadotropine and placentary lactogene) which are at the bottom of placentary dysfunction with the subsequent formation of arrest of development of fetus and perinatal pathology (dystress of fetus). The algorithm of diagnostic and treatment-and-prophylactic actions for frequency decrease incompetent pregnancy and perinatal pathologies at women with metabolic syndrome on the basis of the differentiated approach to use of system and local correction taking into account an index of weight of body is improved and introduced.