Boyko O. Prognostic value of changes in polypeptide regulators of hematopoiesis in patients with myelodysplastic syndrome

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U002237

Applicant for

Specialization

  • 14.01.31 - Гематологія та трансфузіологія

17-05-2016

Specialized Academic Board

Д 26.612.01

State Institution "Institute of Hematology and Transfusiology NAMS Ukraine"

Essay

Objective: improve the efficiency of prognosis and response to treatment of MDS based on the evaluation of the polypeptide stimulators and inhibitors of hematopoiesis serum krovi.Dopovneno scientific data on prognostic factors and total duration of leukemia-free survival of patients with MDS low and high threshold set ryzyku.Vpershe TNF concentrations - alpha, IL-6, VEGF and EPO in the serum of patients with MDS with predictive value for vyzhyvannya.Vstanovleno low probability of obtaining remission in response to immunosuppressive therapy and the development of early relapse in treated patients.

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