Bezugla N. Spatial photometry of biological media

The thesis is devoted to developing the method of photometric analysis of biological media by expansion the space of definition their optical properties. That made possible the simultaneously consider the characteristics of the optical radiation, reflected and transmitted by biological media, within the full solid angle. In the work the main methods of solution the basic equation of radiative transfer theory in problems of optical biomedical diagnostics, were analyzed. On this basis, has developed methods of implementing of the mathematical basis of spatial photometry of biological media by determining the scattering intensity along parallels (circular bands) and meridians (sections). The proposed scheme-technical versions of information-measurement system for spatial photometry along sections with two and eight channel, which were realized in experimental setups of goniometric and spherical type. The interfaces and methods of application of developed software for parallel photometric analysis "IMSOB" and "IMSOB-2", to support research the scattering indicatrix along sections in reflected or transmitted light for two- and eight-channel systems respectively are given. The analysis of the indicatrix of laser light scattering by thick samples of muscle tissue at different wavelengths with transverse and longitudinal placement of fibers was made.For phase function of single scattering the transition from indicatrix scattering of thick sample to the single scattering anisotropy factor g was made. Identity of experimentally-determined values of the optical coefficients of diffuse reflection and total transmission and determined by the results of Monte Carlo simulation using the average values by sections of the anisotropy factor of single scattering are approved.