Katsytadze I. Influence of the different ways of heart rate control on exercise tolerance, its hemodynamic support and myocardial function in chronic artery disease patients with chronic heart failure and moderately reduced ejection fraction

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U002529

Applicant for

Specialization

  • 14.01.11 - Кардіологія

31-05-2016

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The dissertation is devoted to the improvement of therapy, medical control of heart rate in chronic artery disease patients with moderate heart failure and ejection fraction<45 %. The thesis demonstrated that combination therapy of ivabradin and bisoprolol is not inferior than full-doze of bisoprolol therapy on clinical effect and reduce the average daily and maximum heart rate, but does not provide reducing ectopic myocardial ventricles, improves exercise tolerance improvement, longitudinal left ventricular systolic function, has advantages before monotherapy b-AB due to the positive impact on the reduction of PWV and its augmentation.

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