Palamar A. Synthesis and biological activity of 4-thiosubstituted 5-formylimidazoles and their derivatives

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U003133

Thesis Registration Form

0416U003133.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

28-04-2016

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

This dissertation work is dedicated to the search of new biologically active compounds among the derivatives of 4-thiosubstituted 5-formylimidazoles. With this goal preparatively convenient synthesis methods were developed and a series of [(5-formyl-1H-imidazole-4-yl)thio]alkane carboxylic acids derivatives was produced. Pharmacological screening of the produced compounds was performed and a high biological potential of derivatives of [(imidazole-4-yl)thio]acetic(propionic) acids was found; they are characterized by significant antioxidant, antimicrobial, antitubercular, and hypoglycemic activity

Read more

Files

aref.docx

dis.docx

Similar theses

0523U100273

Lozynskyi Andrii V.

Polyfunctional condensed and non-condensed thiazole/thiazolidinone derivatives: directed synthesis, physicochemical properties and biological activity

0523U100081

Safonov Andrii A.

Синтез, перетворення, фізико-хімічні і біологічні властивості похідних 1,2,4-триазолу, які містять тіофен-2-ілметильний замісник

0523U100030

Bihdan Oleksii A.

Synthesis, chemical modification and biological properties of 3-, 4, 5-trisubstituted-1,2,4-triazole-3-thions

0521U101625

Borodina Nataliia Valerivna

Pharmacognostic study of willow plants and creation of medicines based on them. Qualifying scientific work on the rights of the manuscript

0421U102935

Anosova Liydmila Sergееvna

Chemical and toxicological study of clopidogrel