Kholodnyak S. [2-[(3-Аryl-1H-1,2,4-triazol)phenyl]amines: synthesis, chemical modification, physico-chemical and biological properties of the synthesized compounds

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U004114

Thesis Registration Form

0416U004114.pdf

Applicant for

Kholodnyak Sergii Valeriiovych

Specialization

15.00.02 - Фармацевтична хімія та фармакогнозія

Date of defense

06-10-2016

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The present work is devoted to the elaboration of preparative synthetic protocols for 2-R-[1,2,4]triazolo[1,5-c]quinazolines and products of their hydrolytic cleavage – [2-(3-aryl-1,2,4-trazole-5-yl)phenyl]amines. The latter were used as starting compounds for the synthesis of previously unknown N-phenyl-N'-[2-(3-phenyl-1H-1,2,4-triazole-5-yl)phenyl]ureas, N-[2-(3-phenyl-1H-1,2,4-triazole-5-yl)phynyl]benzenesulfamides, 2-aryl-5-R-, 2-aryl-5-R, 5-R1-5,6-dihydro- and 2-aryl-6'H-spiro[(cycloalkyl-, hetero-cyclil-, hetaryl-)]-[1,2,4]triazolo[1,5-c]quinazolines.

Thesis supervisor

Kovalenko Sergiy Ivanovych

Official opponents

Безуглий Петро Овксентійович
Лесик Роман Богданович

Files

aref.doc

dis.doc

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