Salionov V. Synthesis, physico-chemical and biological properties of derivatives of 5-thienyl-4-(alkyl,-aryl)-1,2,4-triazoles-3-thiones

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U004115

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

06-10-2016

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The aim of this work was a target search of new effective and low-toxic biologically active compounds among synthesized for the first time derivatives of 4-R-5-(thiophene-2-yl)-4H-1,2,4-triazole-3-tiones, investigation of their physical, chemical and biological properties, identification of a correlation «chemical structure – pharmacological action» and recommendations for preclinical trials on the most promising compounds of a specified range.

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