Rozumenko I. Relation of the polymorphism of genes inhibitors and activators of ectopic calcification with the development mechanisms of acute coronary syndrome

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U005127

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

30-06-2016

Specialized Academic Board

Д 55.051.05

Sumy State University

Essay

Thesis is devoted to the revealing the influence of the polymorphism of genes inhibitors (K121Q of gene ENPP1 and Т134967G of gene АNКН) and activators (А69314G of gene ТNАР) of calcification on the development of acute coronary syndrome. It is established the frequency of the alleles and genotypes according to the K121Q polymorphism of gene ENPP1, Т134967G polymorphism of gene АNКН and А69314G polymorphism of gene ТNАР in the Ukrainian population. It is found out that the influence of genetic factor on the development of cardiovascular abnormality has gender aspects.

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