Gdanskyi S. Morphofunctional changes in the liver and kidneys in conditions of combined injury.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U000375

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

27-01-2012

Specialized Academic Board

Д 58.601.01

I. Horbachevsky Ternopil State Medical University

Essay

It was established that the combined trauma of the chest and thighs is significant violations organ hemodynamics that appear in the post-traumatic period initially rising vasoconstriction with narrowing and thickening of artery walls of small and medium caliber and simultaneous vasodilation and a compensatory increase in capacity for large caliber arteries expressed venous background in plethora. Further back is their development. This in idex Vohenvorta in renal arteries of small diameter increases by 32 % on the third day of observation, kept at this level for seven days, followed by its reduction to 28 days experiment, continuing to dominate the control level of 9 %. In hepatic arteries such changes are slower and less intense with the growth of this indicator from 168,75 ± 2,47 to 218,33 ± 3,94 and an increase of 29 % on the seventh day of observation and his subsequent decrease to 177,49 ± 4, 45 to 28 day experiment dominated control over the level of 5 %. Simulated pathology is accompanied by a significant increase in the level of endogenous intoxication already on the first day after causing injury. This figure rises to 2.5-3.5 times. In all subsequent periods of observation is their progressive partial reduction, however, even in 28 days, they continue to significantly exceed the reference level.

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