Pashkova I. The brain natriuretic peptide gene polymorphism and plasma concentrations of M - and C - natriuretic peptides in men with essential hypertension complicated by chronic heart failure. Clinical significance.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U000434

Thesis Registration Form

0417U000434.pdf

Applicant for

Specialization

  • 14.01.11 - Кардіологія

28-02-2017

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The dissertation is devoted to the study of the BNP (T-381C) gene polymorphism, the plasma levels of BNP and CNP, changes in the structural and functional state of the heart and systemic hemodynamics in men with EH, complicated by CHF stage II A. It was found that the inheritance of the genotype T381T of the BNP gene in men, 40-60 years is associated with a high probability of CHF stage II A on the background of EH, lower plasma levels of BNP, CNP, more negative structural and functional changes in myocardium.

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Files

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