Lozynskyy R. Diagnostic and prognostic significance of chromosomal abormalities and mutation JAK2V617F in myelofibrosis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U001016

Thesis Registration Form

0417U001016.pdf

Applicant for

Specialization

  • 14.01.31 - Гематологія та трансфузіологія

27-12-2016

Specialized Academic Board

Д 26.612.01

State Institution "Institute of Hematology and Transfusiology NAMS Ukraine"

Essay

Objective: to optimize diagnostic procedures and monitoring the flow of MB patients by determining the karyotype abnormalities and mutations JAK2V617F. Among the anomalies of individual chromosomes with myelofibrosis often observed chromosome monosomy 7 and trisomy of chromosome 8. established that chromosomal abnormalities occurred significantly more frequently in combination with polyploid set of chromosomes than without polyploidy. Found significantly higher incidence of adverse prognostic for DIPSS-Plus cytogenetic abnormalities in patients with mutations JAK2V617F. Medicine.

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Files

aref.doc

autoreferat--aref.doc

dis.doc

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