Chornopyshchuk R. Local immune correction in the combination treatment of infected wounds (experimentally and clinical research).

Object - infected wound; goal – increasing the effectiveness of complex treatment of patients with infected wounds by applying a method of local immunocorrection using the composition of an antimicrobial ointment on a hydrophilic base and an immunomodulator of the muramylpeptide series; methods – experimental, clinical, laboratory, microbiological, cytological, immunological, morphometric, morphological, statistical; results – peculiarities of changes in clinical and laboratory, microbiological, cytological, immunological parameters of blood and wound contents and histological changes in tissues in animals against the background of experimental modeling of the wound process; the diagnostic value of the factor of the neutrophil Form factor was first studied by establishing its correlation with laboratory, bacteriological, cytological, immunological and histological parameters; the composition of the composition of medicinal preparations for local treatment of infected wounds with antimicrobial and immunomodulating action was developed and scientifically justified; In the experimental conditions, the expediency and effectiveness of the use of the proposed composition of drugs in the local treatment of infected wounds; the effectiveness of topical application of the proposed composition in the complex treatment of patients with infected wounds; branch – medicine.