Kotsabyn N. A differentiated approach to improve the implantation potential of the endometrium in women with unsuccessful attempts in vitro fertilization in history

The thesis is devoted to the problem of increasing the efficiency of the IVF program and reduce the percentage of failed attempts of implantation of the embryo. The results of the research of hormonal imbalance, the status of ovarian reserve, sono-, histo - and monogastrics of the endometrium of 105 women of different age groups. Have been installed main reasons of failed IVF attempts, features of hormonal fone and features of synthesis of growth factors VEGF and IGF-1, and immunohistochemical markers of intrauterine pathology. The complex system of diagnostics and differentiated correction scheme of violations of endometrium inferiority were designed and implemented, the strategy of embryo transfer was optimized, which contributed to improve the efficiency of infertility treatment in this category of patients. Branch - medicine.