Sychyk M. Catheter radiofrequency ablation of cardiac arrhythmogenic zones of improved efficiency and safety.

The regularities of the thermal effect of the radiofrequency ablation (RFA) on the areas of the heart, in which standard ablation of of arrhythmogenic sources is perfomed, were established. Adaptive method of calculating the thermoelectric characteristics of myocardium of working human heart was developed based on analysis of individual electrical and thermal parameters of response of heart tissue to the exposure of radiofrequency current. The three-dimensional mathematical model of catheter radiofrequency ablation was developed. It is implemented in clinical practice as a tool for the visualization of depth of destruction and temperature in myocardial tissue for improving of the efficiency and safety of ablation. The practical recomendations of choosing parameters of radiofrequency ablation for different anatomical areas of the heart were developed. The effective technique of catheter bipolar RFA of pathological sources in abnormally thickened wall of the heart was developed, that are not achieved with standard monopolar ablation.