Petropavlovskay V. Tactics of carrying out auxiliary genesial technologies at patients with the excess body weight and metabolic syndrome.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U003855

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

29-09-2017

Specialized Academic Board

Д 26.613.02

Essay

Scientific work is devoted to restoration of genesial function at patients with the excess body weight and metabolic syndrome on the basis of studying at them clinical-functional and endocrinologic features, and also improvement and introduction of algorithm of diagnostic and treatment-and-prophylactic actions with use of auxiliary genesial technologies. The role by excess body weight and metabolic syndrome in genesis of female sterility is investigated. Influence dishormonal (hyperandrogenia) and the dismetabolical of disturbances (a hypersecretion of insulin and leptin) on the clinical course of female sterility is shown. The role of disturbances of secretion of peptide and steroid hormones in genesis of chronic anovulation is presented at various degree by excess body weight and existence of metabolic syndrome. Correlation interrelations between body weight index, a dosage of Gonadotropinums and duration stimulation at patients with the excess body weight and metabolic syndrome are established. It allowed to prove scientifically advanced algorithm of carrying out auxiliary genesial technologies taking into account an index of body weight and existence of metabolic syndrome. Comparative aspects of frequency and structure of disturbances of genesial function at patients with the excess body weight and metabolic syndrome are shown. The most informative markers of a condition of an ovarial reserve and the androgenic status at patients with the excess body weight and metabolic syndrome are presented. Criteria of indications and the distinctive moments of tactics of carrying out auxiliary genesial technologies at patients with various index of body weight and metabolic syndrome are developed.

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