Sobkova Z. Hygienic assessment of the risk of circulation of candidal infection in patients and in the internal environment of a multidisciplinary hospital

The dissertation is devoted to the hygienic assessment of the risk of circulation of candidiasis infection in patients and in the internal environment of a multidisciplinary Nhospital on the basis of complex sanitary-hygienic, epidemiological, microbiological research. The feasibility of microbiological monitoring and preventive measures for intracavitary candidiasis infection in a multidisciplinary hospital was scientifically substantiated. The frequency of selection of yeast fungi of the genus Candida in the biological material of patients was determined and the monitoring of the internal environment (medical equipment, hands of medical personnel, surface, air, etc.) of the hospital regarding the presence of Candida species is carried out. The etiological significance of yeast-like fungi of the genus Candida in the structure of pathogens of intra-hospital infections in the resuscitation and intensive care department (RICD) and their biological properties, in particular: the level of sensitivity to antimycotics, determination of adhesive properties and the ability to form a biofilm to predict the development of fungal infection, has been studied. Conditions for indicating yeast-like fungi of the genus Candida were improved. The most dangerous objects of infection risk and preventive measures are defined. It was shown that in the hospital environment of the intensive care units the risk of infection is the hands of the nurses, devices of artificial ventilation of the lungs, intravenous catheters, air, surfaces, and biological material from the patients. The algorithm of preventive measures in the intensive care and resuscitation departments was developed.