Krolenko K. Synthesis and investigations of the novel biologically active compounds among the series of two- or three-membered assemblies of heterocycles and spiro-systems with piperidine and pyrrolidine fragments

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0418U001223

Thesis Registration Form

0418U001223.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

01-03-2018

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

The thesis is devoted to the synthesis and investigations of the novel biologically active compounds among the series of two- or three-membered assemblies of heterocycles and spiro-systems with piperidine and pyrrolidine fragments. For the purpose of obtaining new biologically active compounds new efficient methods for synthesis of novel substituted 2-(1-acylpiperidin-4(3)-yl)-1H-benzimidazoles, 3-(piperidin-4-yl)quinazoline-4(3Н)-ones, 4(3)-[4-(3-(alkyl/aryl)-[1,2,4]oxadiazol-5-yl)-[1,2,3]triazol-1-yl]-piperidines, 3-(alkyl/aryl)-5-(1-pyrrolodine-3-yl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazoles and 3-alkyl-triazaspiro[4.4(5)]nonane(decane)-2,4-diones were developed.

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Автореферат-Кроленко-К.Ю.pdf

Дисертація-Кроленко-К.Ю..pdf

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