Kolomoiets O. Synthesis, physicochemical and biological properties of 6-mono- and 6,6-disubstituted 3-R-6,7-dihydro-2H-[1,2,4]triazino[2,3-c]quinazolin-2-оnes

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0418U003099

Thesis Registration Form

0418U003099.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

14-09-2018

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The thesis is devoted to the investigation of substituted 6-R-3-(2-aminophenyl)-1,2,4-triazin-5-ones [5+1]-cyclocondenesation with carbonyl compounds and the synthesis of unknown 6-mono- and 6,6-disubstituted 3-R-6,7-dihydro-2H-[1,2,4]triazino¬[2,3-c]-quinazolin-2-ones, 3'-R-spiro[aza/oxo/thiа]cycloalkyl-1(3,4),6'-[1,2,4]triazino¬[2,3-c]qui¬nazolin]-2'(7'H)-ones, N-substituted 3'-R-2',7'-dihydrospiro[indoline-3,6'-[1,2,4]¬triazino[2,3-c]quinazolin]-2,2'(7'H)-diones, for which the physicochemical and biological properties were studied.

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