Kirichenko R. Improvement of predicting the course of myocarditis based on research the parameters of heart rate variability and morphological and functional heart state.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0418U004222

Applicant for

Specialization

  • 14.01.11 - Кардіологія

27-11-2018

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The dissertation is devoted to improving the prognosis of the myocarditis by the based on a comprehensive study of the parameters of cardiac rhythm variability and structural and functional state of the heart, identification the prognostic markers of severe course of diffuse myocarditis. In the dissertation was found that in patients with myocarditis with reduced LV ejection fraction low values of SDNN, SDNN, RMSSD, LF elevation and LF/HF ratio, presence delayed contrast on MRI, detected in the first month from the debut of the disease are predictors of severe myocardial course. Based on the results of dynamic observation, using a discriminat analysis, we built a mathematical model for early prediction of the development of unstable ventricular tachycardia episodes in patients with myocarditis.

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