Horbatiuk I. Optimization of diagnostics and treatment of acute non-streptococcal tonsillopharyngitis in children

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0419U000602

Applicant for

Specialization

  • 14.01.10 - Педіатрія

01-03-2019

Specialized Academic Board

Д 76.600.02

HSEE of Ukraine "Bukovinian State Medical University"

Essay

Object - children with acute tonsillofaringitis; the purpose is to determine the peculiarities of the manifestations of acute nonresponsible tonsillofaringitis to optimize its diagnosis and treatment in childhood; methods - clinical, microbiological, virological, instrumental, laboratory, statistical; results - it has been established that the disease of nonstreptococcal acute tonsillofaringitis, in contrast to the infectious process caused by beta-hemolytic streptococcus group A, is clinically characterized by less pronounced inflammatory-intoxication syndrome; It has been proved that the constellation score for patients with acute tonsillofaringitis (MacAidzeka, Centor, Breese) with marginally low test results (sum of scores <3) is more characteristic for children with nonstreptococcal infection of tonsils and mucus pharynx, and for high - for both variants of acute tonsilopharingitis; It has been proved that after antibiotic therapy in every fourth child in the culture, the stomach from the ovum continued to sow beta-hemolytic streptococcus of group A; found that the use of Streptastest to detect beta-hemolytic streptococcus of the A-infection of the mucous membrane of the tonsils and pharynx for high specificity, combined with a high risk of false-negative results in each second patient with this etiology of the disease; It has been shown that in children who became ill with acute streptococcal tonsillofaringitis during lordinatine monitoring more often than in patients of the comparison group, signs of lowering the tolerance of metered physical activity and the efficiency of regulation of hemodynamics by the autonomic nervous system were determined.

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