Mazchenko O. Prevention of the fetal distress in pregnant women with hypertensive disorders

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0419U000693

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

05-03-2019

Specialized Academic Board

Д 05.600.01

Vinnytsia National Pirogov Memorial Medical University

Essay

Object – fetal distress; purpose – to decrease the rate of distress based on the determination of the level of homocysteine and ox-idative modifection of protein in the blood of pregnant women and to correct metabolical and haemodynamical discharges in the fetoplacental system; methods - psychometric, clinical, laboratory, instrumental, hardware methods, mathematics and statistics; results – It was proved that the leading role in the outbreak of fetal distress in pregnant women with hypertensive disorders is played by hyperhomocysteinemia and an increase in the parameters of spontaneous o[idative modification of the protein that correlates with the violation of the parameters of the biophysical profile of the fetus and utero-placental-fetal blood flow. The mathematical model of the individualized prediction of the fetal condition in pregnant women with hypertensive disorders is cre-ated, which, with high sensitivity and specificity, allows predicting the onset of fetal distress, it was recommended the comple[ matabolical theraphy, that was indices on the preventhion of the perinatal morbidities; branch – medicine.

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