Pilipenko S. Intensive care of neuro-hemodynamic disorders in cancer patients with superior vena cava syndrome.

The dissertation theoretically substantiated and presented a new solution to the problem of diagnosis and intensive care of neuro-cardio-hemodynamic disorders in cancer patients with superior vena cava syndrome, aimed at reducing the number of pre-and postoperative complications and reducing mortality under this syndrome. Based on the study of this problem, it was found that more than 90% of cases leading to superior vena cava syndrome are malignant tumors. Lung cancer accounts for 85%. In most cases, it is small- cell or squamous cell lung cancer. Mortality in SVCS reaches 95%. Based on the study of the frequency and variants of the types of superior vena cava syndrome, it has been found that in lung cancer, SVCS occurs in 84% of cases, in lymphoproliferative tumors 13%, in other types of tumors in 4% of cases. In the preoperative period, disorders of neuro-cardio hemodynamics were determined in 93% of patients with SVCS. Comprehensive use and implementation of the proposed methods of diagnostics and intensive care in patients with SVCS reduced mortality by 1.4 times (P ? 0.05), ischemic brain damage by 1.2 times (P ? 0.05), increased hemodynamic stability by 2.7 times (P?0.05).