Levchenko D. Improvement of surgical treatments efficiency in patients with nephrolithiasis by using micro- and ultra-minipercutaneous nephrolithotripsy.

The dissertation is devoted to the actual problem of clinical urology - to increase the efficiency of miniinvasive surgical treatment in patients with nephrolithiasis using a differentiated approach to the selection and optimization of methods, taking into account the clinical form of the disease. The concept of choice and objectified indications for the implementation of various technologies of minimally invasive surgical intervention, including micro-and ultra-miniPNL in various clinical forms of nephrolithiasis and assessment scale of the degree of renal parenchyma injure, has been developed. The use of a diagnostic marker - cystatin C - is proposed for determining the degree of sub-operative damage to the kidneys parenchyma in patients with nephrolithiasis, which allows to predict the complications in early postoperative period. The algorithm of choice for minimally invasive treatment methods in patients with nephrolithiasis has been developed.