Sokolova O. Pharmacognostic study of sunflower (Helianthus annuus L.) herbal drugs and the development of herbal medicinal products on its basis

The thesis is devoted to the pharmacognostic study of domestic herbal drugs of sunflower and the development of medicinal products on its basis. The qualitative composition and quantitative content of BAS in flowers, anthodiums, and leaves of the sunflower plant have been studied, namely phenolic compounds, carbohydrates, carboxylic acids, essential oil components, carotenoids, and minerals. A total of 99 substances have been identified in herbal drugs, lipophilic fractions, water-alcohol extracts, and essential oils. Techniques for identification of flavonoids and hydroxycinnamic acids by the method of TLC, quantification of total flavonoids, total hydroxycinnamic acids and total carotenoids by the method of spectrophotometry have been developed. Draft monographs "Sunflower Flower" and "Sunflower Leaves" have been developed. Technologies for producing a dry extract from anthodiums, a lipophilic extract from flowers, and a tincture from leaves have been developed. Drafts of Quality Control Methods for herbal drugs and substances have been developed. An antimicrobial effect of a dry extract from anthodiums, a lipophilic extract from flowers, and a tincture from leaves, as well as a choleretic effect of a dry extract from anthodiums of the sunflower plant, have been established.