For the first time the efficiency of the competence for future physicians' chemical safety (CforFPCS) forming model in the process of teaching bioorganic and biological chemistry is theoretically substantiated, developed, tested and experimentally confirmed in the dissertation and the method of its implementation is revealed. A comprehensive analysis of scientific and methodological sources and international regulatory documents on current concepts in the field of chemical safety was made. The definition of the "chemical safety" concept as a set of regulatory and practical measures that minimize the negative impact of chemicals during their production, storage, transportation, sale, use and utilization through concerted work in the fields of legal, economic, environmental and educational activities was concretized. As a result of the analysis, the components of chemical safety, necessary for the professional training of future physicians were identified: understanding that a chemical factor is an integral danger to human health; knowledge of methods of marking chemical products; adherence to chemical safety measures throughout the life cycle. The potential of the "Biological and bioorganic chemistry" discipline in the formation of CforFPCS is substantiated. It is caused by a combination of theoretical preparation and laboratory practicum. The biochemical preparation of future physicians in the context of modern concepts of chemical safety experience's analysis results revealed the urgent need for the development of theoretical and methodological foundations of CforFPCS formation in the process of teaching bioorganic and biological chemistry. The future physician's chemical safety competency has been found to be an integral personality trait that characterizes the willingness to collect, analyze, interpret current data on biochemical mechanisms of the effects of chemicals on human health, and to use the skills and knowledge to safely handle the chemical compounds in the course of their life cycle for the purpose of successful therapeutic and prophylactic activities. The content is substantiated, the structure, criteria, indicators of CforFPCS in the process of teaching bioorganic and biological chemistry and the levels of their formation are developed. At the CforFPCS structure were distinguished: the motivational value; cognitive; active components. Requirements for indicators and levels (low, medium, sufficient, high) of motivational-value, cognitive and activity criteria of chemical safety competency are determined. A model of CforFPCS formation was developed, in the structure of which three interconnected blocks were distinguished: theoretical and methodological block - the purpose of research, work tasks, didactic approaches and principles, pedagogical conditions of formation of competence on chemical safety were substantiated; organizational and activity block - methods, means and forms of organization of educational activity are selected, stages of competence formation are considered; control and evaluation unit - presents the types, forms of control, diagnosis of competence levels. The method of realization of the CforFPCS formation model of future doctors in the process of teaching bioorganic and biological chemistry is described. It involves the use of modern methods of teaching, teaching aids, individual and group activities for students. Experimental verification of the competence forming model performance for chemical safety of future physicians in the process of teaching bioorganic and biological chemistry and the method of its realization were carried out. The validity of the results obtained was confirmed by the Pearson test.