Sinichenko A. Pharmacognostical research of cultivated species of the genus Primula L.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0420U101268

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

18-09-2020

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The systematic pharmacognostical study of over ground and underground organs of three cultivated species of the genus Primula L. (drumstick primrose – Primula denticulate Smith, Julia’s primrose – Primula juliae Kusn., rock primrose – Primula saxatilis Kom.) was carried out for the first time. For the studied objects, we have determined qualitative and quantitative composition of the major groups of BAS: ascorbic and organic acids, carbohydrates, amino and fatty acids, phenolic substances (hydroxycinnamic acids, flavonoids, coumarins, condensed tannins, anthocyanins), triterpenoid saponins.The systematic macro- and microscopic analysis of drumstick, Julia’s and rock primroses stem, flower, leaf and rhizomes with roots was conducted at the first time and main diagnostic features of their morphological and anatomical structure were determined. Dense extracts from drumstick primrose leaves and rhizomes with roots were obtain. The projects of quality control methods for the new medicinal plant raw materials and substances obtained from the leaves and rhizomes with roots of drumstick primrose were elaborated.

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