Parashchuk E. Pharmacognostic study of burnet saxifrage (Pimpinella saxifraga)

The thesis is devoted to the study of a valuable medicinal plant from the family of celery (Apiaceae) burnet saxifrage (Pimpinella saxifraga L.). Complex pharmacognostic analysis of herb and rhizomes and roots of the studied plant was carried out and the qualitative composition was determined and the quantitative content of biologically active substances was identified: amino acids, polysaccharides, hydroxycinnamic acids, flavonoids, coumarins, tannins, fatty and organic acids, saponins, essential oil. The elemental composition of the above-ground and underground organs of the plant were determined. The fractions of water-soluble polysaccharides (WSPS) and pectic substances (PS) in the herb and rhizomes and roots of burnet saxifrage were distinguished, the quantitative content of which was: WSPS – herb – 6.95 %, rhizomes and roots – 11.25 %; PS – herb 11.89 %, rhizomes and roots – 4.41 %. The GC/MS method determined the monomer composition of polysaccharides of the studied plant. The composition of polysaccharide complexes of rhizomes and roots revealed 5 sugars, of which 2 were identified; in the herb – 13 sugars, identified – 3. In both samples of the raw materials D-glucose and sucrose were identified. Macro- and microscopic analysis of the burnet saxifrage herb and rhizomes and roots was performed, the main diagnostic features of their morphological and anatomical structure were determined. Acute toxicity of dense extracts from herb and rhizomes and roots of the burnet saxifrage was established.