Isaienko S. Clinical and psychopathological patterns of suicidal behavior in oncological patients. Modern system of psychoprophylaxis

The purpose of the current research was studying the clinical and psychopathological features of depressive disorders and mechanisms of suicidal behavior in cancer patients for development a personalized system of psychoprophylaxis. It was conducted a comprehensive examination of 154 patients of both genders with extracerebral cancer location and with depressive disorders diagnoses. The main group consists of 103 patients who participated in the developed program for the correction of depressive disorders and prevention of suicidal behavior; control group - 51 patients who received standard antitumor therapy. It was found that the clinical picture of depressive disorders in the examined patients is anxious (28.1 ± 1.3% of patients with lung and bronchial cancer, 24.5 ± 1.2% with cancer of the esophagus, stomach and pancreas, 24.6 ± 1,2% with cancer of the oral cavity and pharynx and 22.8 ± 1.3% of patients with breast and genital cancer), emotionally labile (22.4 ± 1.2%, 28.2 ± 1.3%, 26.1 ± 1.3% and 23.3 ± 1.2% of patients, respectively), asthenic (22.9 ± 1.2% of patients with lung and bronchial cancer, 21.2 ± 1.2% with cancer of the esophagus, stomach and pancreas, 30.5 ± 1.3% with cancer of the oral cavity and pharynx and 19.4 ± 1.1% of patients with cancer of the breast and genitals) and apathetic (21.2 ± 1.2%, 24.7 ± 1.3%, 22.1 ± 1.2%, 32.1 ± 1.4%) variants of psychopathological symptoms. Patients with anxiety and emotionally labile variants of depression have a high level of suicidal risk. The present study showed that the biggest suicidal activity is observed in patients with cancer of the esophagus, stomach and pancreas. Peaks of suicidal activity in patients with oncological pathology have been identified. A model of formation of depressive disorders and suicidal behavior in patients with oncological pathology has been developed. А program of personalized psychotherapeutic support and prevention of suicidal behavior in patients with oncological pathology, which is based on the integrated use of psychotherapeutic and psychoeducational interventions using E-Mental Health technologies, has been developed and tested.The effectiveness of using online psychotherapeutic support of an oncological patient has been proven.