Martovlos A. Clinical and experimental substantiation of stabilization results of orthodontic treatment of patients with dental anomalies and generalized periodontitis

The dissertation work is devoted to increasing the efficiency of stabilization results of the active orthodontic treatment period of dental anomalies (DA) in orthodontic patients with the generalized periodontitis (GP) diagnosed in the retention period with an infraction of bone tissue mineral density.At the experimental stage of the study, a model of systemic osteoporosis, in particular the bones of the alveolar process, was created. According to the biometric study, a significant increase in the height of the bone tissue of the interdental and interradicular septa was observed in the group of animals receiving a general drug based on glycosaminoglycans (GAG) «Teraflex®». The presence of CS in the gel composition in combination with low-intensity laser radiation at a local level enhances the reparative capacity of the bone tissue of the alveolar process, as well as reduces the retention period in the treatment of orthodontic pathology by half. In addition, the presence in the gel composition of such agents as povidone-iodine, metronidazole and chlorhexidine bigluconate additionally creates a stable antibacterial and anti-inflammatory effect. Thus, the application of the treatment-prophylactic complex for stabilizing the results of the active period of orthodontic treatment for the 3 years retention period allowed to trace its high clinical efficiency. According to the results of ultrasound echoosteometry, it was found that after 6 and 12 months in patients of the 1st subgroup the indicators of the frontal area of the mandible were 13.28 ± 0.30 μs and 13.42 ± 0.32 μs, which was close to the indicators of healthy subject group.