Koliadzyn T. Pharmacognostic research of Astrantia major L.

The quantitative content is determined in Astrantia major L. herb: the sum of polyphenols; the sum of flavonoids (from 3.67 % to 5.36 %); oxidized polyphenols; ascorbic acid; free organic acids; the sum of hydroxycinnamic acids , depending on the type of raw material, the place of growth and the phase of vegetation. For the first time, flavonoids are separated into the components and quantified by the method of high performance liquid chromatography. The qualitative composition and quantitative content of volatile compounds are determined by chromatography-mass spectrometry. Fifty components are identified among the volatile compounds of Astrantia major L. herb, the main terpenoids are the following: verbenol, 1,2-dimethyl-1,4-cyclohexadiene, thymol, cariofilen, trans-α-bergamotene, β-farnesene, germacrene D, α-farnesene, bicyclogermacrene, spathulenol, caryophyllene oxide, isoleden, calaren, hexahydrofarnesil acetone. For the first time it is discovered that Astrantia major L. herb contains the following fatty acids: palmitoleic, palmitic, linoleic, 6,9,12-octadecatrienoic, ricinoleic, stearic, behenic, lignoceric. Herbal drugs have a number of advantages over chemotherapeutic ones.