Sokolova K. Optimization of tactic of diagnostics and treatment of dysplasia of epithelium of cervix uterusus.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U000028

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

19-02-2021

Specialized Academic Board

Д 26.613.02

Essay

Dissertation work is devoted increase to efficiency of diagnostics and treatment of ephithelial dysplasia of cervix uterusus for women with papillomavirus of human and bacillosis on the basis of study of new aspects of pathogeny and improvement of algorithm of diagnostic and treatment-and-preventive measures. It is set at the estimation of results of the algorithm improved by us, that exactness of prognosis of positive result of treatment at "regressive" immunophenotype is 96%, and exactness of prognosis of negative result at "progressive" immunophenotype - 92% accordingly. Determination of types of immunophenotype represents the aggressiveness of virus of papilloma of human and possibility of organism of women with ephithelial dysplasia of cervix uterus on background the virus of papilloma to regression and convalescence at the use of the algorithm improved by us. Efficiency of the algorithm improved by us for women with ephithelial dysplasia of cervix uterusus on the virus of papilloma of human and bacillosis is 40%. Among the cured patients at 88-92% took place "regressive" immunophenotype, and among women with "progressive" immunophenotype efficiency of treatment made from 4 to 8% accordingly.

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