The dissertation is devoted to the improvement of the system of ragweed pollen pollinosis prevention. In order to achieve this goal, were used the monitoring of ragweed pollen amount in Zaporizhzhia city using the volumetric method from 2006 to 2016. The obtained daily samples from August to October were analyzed and the number of ragweed pollen grains were determined. The annual features of pollination of this plant were established and compared for further processing the data and establishing the relationship between the amount of ragweed pollen and weather factors. It is proved that the concentration of pollen in the atmospheric air gradually and slowly increases from the beginning of flowering, and at mass flowering of ragweed reaches a maximum. It is established that the combination of meteorological features of the year that is favorable for the flowering of anemophilous plants can significantly increase the concentration of ragweed pollen in the air of Zaporizhzhia relative to the annual average, and the unfavorable combination, in turn, can significantly reduce the level of pollen of this plant compared to the amount expected during this period. It is noted that the analysis of ragweed concentration, taking into account changes in weather conditions before the certain day, allows to make more accurately prediction of the aeroallergenic situation caused by pollen of this plant, which will further improve preventive measures to prevent allergic diseases in the population. The dependence coefficient of ragweed pollen amount in the air on the atmospheric pressure was calculated. It is noted and practically proved that the amount of pollen increases with the weather, when the atmospheric pressure also decreases. The effect of wind on the change in the amount of ragweed pollen in the ambient air has been investigated. We established that usually an increasing of pollen grains observed during the strengthening of the wind compared to the previous day. The effect of precipitation on the change for pollen in the ambient air were calculated. The significant dependence of the change in the concentration of ragweed pollen in the air on the amount of precipitation has been proved - increasing of the ragweed concentration at low rainfall and reducing it only in heavy rainfall. The dependence of the amount of ragweed pollen on the relative humidity was determined. It was noted that more pollen was determined at low humidity, when the humidity decreased in recent days. The necessity to consider the correction of the asymmetry of ragweed pollen distribution on the days of pollination is because after the mass ejection, the pollen does not immediately settle on the substrate, and for some time flies in the air. It is noted that in connection with this feature, even after passing the period with the maximum concentration of pollen grains in the air, in the presence of favorable weather conditions, ambrosia can for a long time be a danger for people with sensitization. It is proposed to evaluate the threat level for people with allergy to ragweed pollen on a 5 point scale, in which 1 point will indicate a low threat level, 2 points will correspond to a high level of danger, 3 points - a medium level of threat, 4 points - high, and 5 points for the highest level of danger for patients. The algorithm for forecasting of the aeroallergenic situation with considering changes in meteorological conditions and average values of pollination has been developed. Testing of the computer program "ANDROID widget for predicting pollen concentration in the air of Zaporizhzhia" was developed and conducted. The research outcomes are of practical interest for hygiene, allergology and prove that early warning of the population about a dangerous aero-palynological situation is possible only considering meteorological factors and other factors that can influence the change of the amount of ambrosia pollen in the air. The relationship between changes in the amount of pollen in the air and changes in weather conditions has been experimentally investigated and substantiated. To improve the prevention of pollinosis, based on the created algorithm, the software product "ANDROID-widget for prediction of pollen concentration in the air of Zaporizhzhia" was developed and manufactured, which can be introduced into the activity of allergists doctors.
