Huzio N. Pharmacognostic study of the common agrimony (Agrimonia eupatoria L.)

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U101566

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

16-04-2021

Specialized Academic Board

Д 35.600.02

Danylo Halytsky Lviv National Medical University

Essay

Objects - leaves, flowers, stems, steamed grass, water and water-alcohol extracts, biologically active substances, resource reserves; purpose - The aim of the work was the pharmacognostic study of the soaring of the common and to establish the possibility of creating drugs based on biologically active substances of the studied raw materials; methods - morphological - description and identification of the common steam; microscopic (scanning electron microscopy) - to establish anatomical diagnostic features of raw materials; histochemical - establishment of the place of localization of BAS in plant raw materials; physicochemical - thin layer (TLC) and paper (PC) chromatography, high performance liquid chromatography (HPLC), spectrophotometry in the UV and visible regions of the spectrum, atomic absorption spectrophotometry (AAS), chromato-mass spectrometry and syrometry B - identity substances; physical - determination of weight loss during drying, total ash, solubility; technological; pharmacological; resource studies. Processing of experimental data was performed using mathematical and statistical methods; results - the quantitative content of BAS in the grass of the common steamer was identified and established depending on the place of growth; the optimal technological parameters of obtaining extracts from the grass of steamed common grass were developed, extracts were obtained and their standardization was carried out, their pharmacological action was studied; morphological and anatomical diagnostic signs of the grass of the common soar have been established; places of growth are revealed, productivity is established. The dynamics of BAR accumulation in the grass of the studied object depending on the vegetation phase and place of growth was studied. The places of growth of common steam in the territories of Vinnytsia, Zakarpattia, Ivano-Frankivsk, Kirovohrad, Lviv, Ternopil and Khmelnytsky regions and its reserves in Ivano-Frankivsk and Ternopil regions on specific thickets have been established. biological stock of raw materials .; introduced - in the scientific and educational process of higher education institutions of pharmaceutical and medical profiles; branch - pharmacy.

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