Tomarovska L. Chemical-toxicological research of Atomoxetine

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U101637

Thesis Registration Form

0421U101637.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

21-04-2021

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

Procedures for identification and quantification of Atomoxetine in biological objects by HPLC-UVD, GC-MS and GC-PID, UV spectrophotometry and extraction spectrophotometry in the visible region of the spectrum with azo dyes methyl orange and the derivative have been developed. The conditions for detection of Atomoxetine and products of its biotransformation in urine by TLC were developed for the first time. The identification of Atomoxetine metabolites excreted in the urine was performed by mass spectrometry. The algorithm for toxicological analysis of biological material and biological fluids for the presence of Atomoxetine, suitable for use in forensic toxicology and clinical toxicology

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Files

autoreferat-aref_tomarovskaja_-16.03.pdf

disertacija-tomarovska-l.ju..pdf

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