Antonenko Y. The impedance spectroscopy system for biological fluids and suspensions

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U102235

Applicant for

Specialization

  • 01.04.01 - Фізика приладів, елементів і систем

07-05-2021

Specialized Academic Board

Д 64.051.02

V.N. Karazin Kharkiv National University

Essay

Antonenko Ye. The impedance spectroscopy system for biological fluids and suspensions. – Manuscript. The thesis for scientific degree of candidate of physical and mathematical sciences, specialty 01.04.01 - physics of devices, elements and systems. – V.N. Karazin Kharkiv National University, Kharkiv, 2021. The thesis is devoted to the development and approbation of an impedance spectroscopy system for the analysis and measurement of the electrophysical properties of biological materials, liquids and suspensions. Suspensions of metal nanoparticles were investigated by impedance spectroscopy, and the efficiency of the indirect method of measuring the mass fraction of metals in an aqueous suspension was confirmed. The efficiency of the method of impedance spectroscopy for rapid analysis of nativeness and measurement of fat content of biological samples and dairy products is shown. The possibility of estimating the concentration of the components of the solution, according to electrical conductivity and dielectric constant, antibiotics amoxicillin and doxycycline with metal salts has been experimentally proved. The method of impedance spectroscopy is used to control the freezing zone during cryodestruction of biological tissues. The dispersion of the dielectric constant of biological tissues and fluids was studied by the coaxial probe method. A miniature microstrip resonator for measuring electrophysical parameters of materials with one-way access has been developed. The efficiency of the coaxial resonator method for control and measurement of electrophysical parameters of liquids in a stream is shown. The main purpose of the developed system and methods are rapid analysis of physicochemical parameters of liquids and optimization of technological processes in pharmacy, biotechnology and chemical industry. Keywords: impedance spectroscopy, Fourier transform, dielectric constant, amplitude-phase detector, three voltmeter method, coaxial probe, coaxial resonator, microstrip resonator, biological fluid, suspension.

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