Kurbanov T. Diagnostics, prevention and surgical treatment of critical increase in tissue pressure in deep burns.

The dissertation is devoted to improving the results of treatment of patients with deep burns by improving diagnostic methods, preventing compartment syndrome and developing original methods of surgical intervention and optimization of the wound process in order to eliminate interstitial pressure and restore the skin. The dissertation consists of experimental (18 rats) and clinical (208 patients) with deep circular burns of the extremities. The original device and technique on animals created a circular deep burn of the extremities and performed necrofasciotomy with the introduction into the adjacent tissues of OFR, which allowed to morphologically confirm the feasibility of the earliest use of these techniques. A set of treatment and diagnostic methods, including dynamic VTT, original necrofasciotomies, examination of the main components of immunity, assessment of cellular elements of cytograms and local ozone therapy, was used in the clinic in 80 victims of the ІІ main group with deep burns. When comparing the results of treatment of patients of the ІІ main group with the comparison group 62 victims traditionally treated, it was found that the proposed methods provide a significant improvement in autodermograft engraftment by 96.5%, reduce the number of surgical interventions by 18.7%, and reduce terminological rehabilitation of patients by 8 4 bed-days. Thus, a set of original methods for the diagnosis of COPD and necrofasciotomies with local ozone therapy was developed, which significantly accelerated and improved the results of treatment of victims with deep burns. Key words: burns, diagnosis of the depth of the lesion, compartment syndrome, local and surgical treatment.