Hrynenko O. Surgical treatment of hepatocellular carcinoma with tumor portal vein thrombosis

The dissertation is devoted to the improvement of the results of surgical treatment of patients with hepatocellular carcinoma complicated by tumor thrombosis of the portal vein by creating, substantiating and implementing new methods of resection and reconstruction of the portal vein. In order to improve the results of surgical treatment of hepatocellular carcinoma with tumor thrombosis of the portal vein, three methods of resection and reconstruction of the portal vein have been proposed – wedge-shaped excision of the portal vein wall with transverse suture, excision of the portal vein wall with autovenous plague and resection of bifurcation of portal vein and portoportal anastomosis by end to end fashion. The study is based on the analysis of the results of treatment of 154 patients with hepatocellular carcinoma, who for the period from 2002 to 2016 underwent 164 radical surgeries and 25 patients who underwent exploratory laparotomy. It has been established that radical surgery, which includes major or extended liver resection with mandatory total caudal lobectomy and resection and reconstruction of the bifurcation and trunk of the portal vein, is an effective and safe method of treating patients with hepatocellular carcinoma, complicated by tumor thrombosis of portal vein.