Vasyl'yev D. Voltage-gated potassium currents of neurons of rats: ontogenesis and role in inhibitory synaptic transmission

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U000389

Thesis Registration Form

0499U000389.pdf

Applicant for

Specialization

  • 03.00.02 - Біофізика

23-02-1999

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

Mean densities of A- and DR- currents of DRG neurons increased while mean density of K-current decreased during first five days of postnatal development and did not change thereafter. Further investigation showed that in TTX-containing solution changes in potassium conductance of a single presynaptic terminal of cultured hippocampal neurons due to action of potassium channel blockers TEA or 4-AP lead to the increasing of the mean quantal content of transmitter release and did not change the value of a single quantum.

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