Slyusarenko G. Express-assessment for chemical factors of water and air environment using erythrocital model

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U001098

Applicant for

Specialization

  • 14.02.01 - Гігієна

14-05-1999

Specialized Academic Board

Д 26.604.01

Essay

Thr dissertation is devoted to the development of methodological approaches to using model erythrocyte for hygienic determination of toxicological action of water and air chemical factors. The follows methods were used: method of determination of acid resistance of erythrocytes, method of contents determination for oxy-, desoxy- and methemoglobulin and Ames express-method. The approaches are elaborated for model erythrocyte as additional ways for hygienic assessment of surrounding factors (for example 19 chemical substances - water and air contaminators, Dnipro water samples during different stages of water preparation and aerosol part of atmospheric air samples from some Ukrainian sites). Calculated method of hemotoxic parameters has been proposed. This method allows to determine minimal hemolytic concentrations. These parameters would be used as additional characteristics for assessment of hemolitical substances.

Similar theses