Makovets'ka O. Biologically active substances of Hypericum L. genus as a source of creation of pharmaceuticals with given properties.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0502U000167

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

26-04-2002

Specialized Academic Board

Д 26.613.04

Essay

3. The thesis is devoted to questions of complex study of Hypericum genus biologically active substances. The new sources of raw material of Hypericum for production of preparations with anti- depressant and anti-virus action - species from Adenosepalum, Hirtella, Taeniocarpium, Coridium sections are revealed. The new compounds of in dianthronic nature with given properties (solubility in water, small toxicity and high biological effect inde- pendent of light influence), - dianthrones water-solu- ble forms and glycosides are modelled and received; their anti-virus action is investigated. Methods of quality control of the first home antidepressive phyto- preparate and complex technology is developed.

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