Pypa L. Toxoplasmotic infection in children: peculiarities of clinic, diagnosis and treatment.-

3 Obiect of this research are children of 0 till 16 years olc with congenital and acquired toxoplasmosis, mothers oi newbom children w ith congenital toxoplasmosis, pregnam women with detected specific antibodies The aim of the re- search i s t o i mprove t he q uality o f d mgnostics a nd e ffici-ency of toxoplasmosis treatment in children of various age groups on the basis of studying its clinical and morphologic 'manifestations, dynamics ofhumoraL cellular immunity rates, levels of y-mterferon, IL 10 and determination ofavidi-' ty of specific antibodies of IgG class The methods of the ' research are clinical, serologic, molecular, genetic, morpho-' logical, statistic The innovation of the research is the ex-' tension of toxoplasmosis pathomorphogenesis, detection of immunogenetic risk markers of toxoplasmosis, confirmati-^on of efficiency of Fansidar m treatment of toxoplasmosis "in children, taking into account acetylation phenotype and determination of antibodies of IgG class for differentiation ppf initial infection from chrome reactivation The result of "the research is the improvement of diagnostics, treatment of ^toxoplasmosis m children and prognosis of its course The outcomes are introduced at a branch level in the field ~, of protection of health