Panasenko O. Synthesis, transformation, physicochemical and biological properties of amino- and thioderivatives of 1,2,4-triazole.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0505U000328

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

12-05-2005

Specialized Academic Board

Д 26.613.04

Essay

The main aim of the dissertation is the synthesis of new high-performance and low-toxic compounds with potential antimicrobial, antifungal, antiviral, neuroleptic, diuretic, anti-inflammatory, anabolic, tocolytic, analeptic, wound healing and anti-ischemic activities among the derivatives of 1,2,4-triazole-5-ilthions and 4H-4-amino-1,2,4-triazole, establishing of regularity of ties between chemical structure and biological effect and application of new effective drugs on basis of derivatives of 1,2,4-triazole to practice.

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