Khaytovych M. The mitochondrial insufficiency in children with vegetative dysfunctions: diagnostic and treatment.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0506U000103

Thesis Registration Form

0506U000103.pdf

Applicant for

Specialization

  • 14.01.10 - Педіатрія

16-02-2006

Specialized Academic Board

Д 26.003.04

Bogomolets National Medical University, Ministry of Health of Ukraine

Essay

The thesis is devoted to the problem of improvement in diagnosis and treatment efficiency of vegetative dysfunctions in children. It was established that secondary mitochondrial insufficiency is one of the important link of the vegetative dysfunctions pathogenesis, arising on the basis of mitochondrial oxidative stress on the background of excessive activity of sympathoadrenal and/or renin-angiotensin-aldosterone system, a free radical oxidation augmentation, reduction in the oxidnitrogensyntase function of endothelium, oxidative damage of mitochondrial DNA, mitochondrial respiration disorder and compensatory intensification of non-mitochondrial energy production. The differentiated therapeutic schedules were elaborated by including the drugs with nootropic, antioxidants, oxidnitrogenmodulating and hypotensive actions.

Read more

Files

aref.doc

aref_tit.doc

титульний.doc

частина1.doc

частина2.doc

частина3.doc

частина4.doc

частина5.doc

Similar theses

0524U000114

Svitlana Nykytyuk

Lyme borreliosis in children: clinical, epidemiological and immunopathogenetic features, diagnosis, treatment and rehabilitation measures

0524U000105

Zavgorodnyaya Natalya Yu

Exogenous and endogenous risk factors for metabolic-associated fatty liver disease in children: criteria for early diagnosis and prognosis

0523U100241

Olena V. Mozyrska

Atopic dermatitis in children with pattern recognition receptor gene polymorphisms: clinical course, treatment, and prognosis depending on sensitization profile

0523U100134

Iryna M. Sarapuk

Neonatal integrated neuro-developmental care for preterm infants: prerequisites, components, their pathogenetic mechanisms, early and long-term outcomes

0823U100499

Tytusa Andrii Vasylovych

Subclinical calcium deficiency in children of early school age: ways of formation and correction.