Chinov G. Chlamydia trachomatis and Trichomonas vaginalis infections in combination with opportunistic pathogenic bacteria (clinical displays, features pathogenesis, treatment and preventive maintenance)

Dissertation is devoted to an actual scientific problem - development of medical, preventive and organizational actions for struggle with mixed genital infection. Epidemiological features and character of clinical displays of the mixed infection was established. Specific structure and sensitivity to antibiotics of the pathogenic bacteria revealed at persons with venereal infection are studied. The algorithm of diagnostics was developed. Immunopathology of the mixed infection, character of change of a cytokine level was elucidated. The degree and character of reproductive dysfunctions were studied and the functional conditions of a hormone system were characterized. Psychosomatic problems at the mixed venereal infections were described. The effective method of treatment with modern antibiotics, and the means of protection of an organism from an infection are developed. The mathematical model of distribution of venereal infections in a population was created. Economic criteria of screening on venereal infections are developed. The sexual behaviour of various age and social groups and their influence on venereal infections distribution was investigated. The complex of preventive and organizational actions for struggle against the mixed venereal infection at the central and regional level was offered. The implementation of these actions could improve essentially treatment and preventive maintenance of infection, caused by C. trachomatis, T. vaginalis and concomitant pathogenic bacteria.