Petrushenko V. Intensive Care and Surgical Correction in Steril and Infected Pancreonecrosis (clinic-experimental examination)

Object - aseptical and infected pancreonecrosis; methods clinical, bio-chemical, immunological, microbiological, morphological, instrumental, experimental, special, calculation systems of estimation of weight the states, statistical; novelty it is first set in an experiment, that on the initial stages of AEN pankreocytis perish by an apoptosis; it is first proved that early (6-12 hours) application of complex immunepathogenetic of the grounded therapy of NP with the use of preparations with expressed anti-cytokine and immunestimulant action reduces the level of circulatory inflammatory cytokine; the optimum concentrations of PCT are first certain for diagnostics of infected PN and realization of estimation of clinical meaningfulness of determination of PCT of blood; clinically and expedience is experimentally grounded the use of immunemodulators in treatment of NP; well-founded testimonies to the opened operations for the patients of NP; testimonies and methods of operative treatment of patients ofANP and miniinvasive treatments of patients are certain infected NP; results – the results of treatment of patients aseptical and infected pancreonecrosis are improved by determination new pathogenetic grounded diagnostic and treatment-tactical approaches; branch – medicine.