Vansovych V. The pathogenesis, prognostication, prophylaxis and treatment of peritoneal adhesion (clinical and experimental research).

Object - patients which after laparotomy had PA, patients at which the displays of PA absent after laparotomy; rat of line Vistar with experimental PA; methods – biophysical, histochemistry, vehicle, cytogenetical, statistical; novelty – first in experimental researches a role is set chronic emotionally pain stress in conditioning for the origin of PA and ability of chronic stress to be instrumental in realization of the N-acetyltransferases inherited, related to activity is set, by inclination to excessive adhesion; new information is got about the role of the state of heterospecific resistance in forming of the purchased inclination to excessive adhesion and the mechan-isms of its realization are set; extended presentation at the thiol- dependent mechanisms of forming of propensity to the origin of PA or its relapse; the features of changes of genetic vehicle of somatic cages are first set at PA; a picture is extended of possibility of the use of антиоксидантных and antioxidative preparations for a prophylaxis and treatment of PA of peritoneum; results – efficiency of methods of prophylaxis of adhesion is enhanceable after abdominal operations and the results of surgical treatment of patients are improved with complicated SB by development on the basis of got these methods of prognostication, prophylaxis and treatment of SB; an area is medicine.; branch – medicine.