Yeroshenko G. Structural organization of major salivary glands at the sympathetic and parasympathetic departments of the vegetative nervous system stimulation.

Dissertation is devoted determination of structural changes of major salivary glands at the terms of stimulated salivation. Rat's major salivary glands were object of research. Revealing of histofunctional futures of rat's major salivary glands in condition of stimulated secretion, to give a theoretical substation of the mechanism of saliva's formation after introdution of adrenaline and acetylcholine and to difine structural preconditions of optimal ways of adequate maintenances of humidifying of an oral cavity was a research aim. In work have been used histologic, histochemical, morphomethric, electronomicroscopic methods, and method of serial semithin sections, graphic reconstruction and the correlation analysis. New information is got about influence of adreno- and cholynomimethics on a haemomicrovascular rate. It is set that on the microvessells of parotid and sublingual glands it's operated as synergetic, but give an opposite effect. In a submandibular gland for an exchange link their influence is synergistic, and for a capacity - antagonism. It is well proven that at stimulation in the parotid glands of rats there is strengthening of secret-formation and extrudes of granules in eventual departments. For the glands of the mixed secretion on both stimulators the increase of liquid transports determined from to the interstitium to the road clearances of the duct's system. At acetylcholine introduction there are the expressed changes of representation and localization of leucocytes and tissue basophiles in composition of particles of major salivary glands, which are morphological confirmation of ambiguous influence of cholynomimethics on local immunity of the oral cavity. Conducted a cross-correlation analysis set predominance of the closely-coupled interfaces for the ductal system in sublingual and submandibular glands, that confirms them leading role in forming of liquid part of the stimulated saliva. Basic structural signs and metrical indexes can be utilized in quality criteria at the estimation of the morphofunctional state of salivary glands at pathoanatomical researches with the purpose of the deep understanding of the diseases and syndromes, which are, accompanied dysfunction of salivary glands known in clinical stomatology. The results of investigation introduced to teaching and scientific processes