Lugovskov A. Pathogenesis of disturbances at hepatitis A and their correction in residents of the industrial region

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0512U000408

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

18-05-2012

Specialized Academic Board

Д 29.600.02

Essay

The thesis is devoted to the study of the pathogenesis of viral hepatitis A and correction of disturbances in residents of the industrial area (Lugansk region). Immune and metabolic disorders in vitro in monocytes, T-helpers/inductors and cytotoxic T-suppressors of peripheral blood of patients with viral hepatitis A are studied for the first time. Immune, metabolic and microcirculatory changes are studied in the patients with viral hepatitis A. The tactics of urgent chemoprophylaxis of hepatitis A with usage of endogenous interferon production inductor amizonum is pathogenetically and epidemiologically substantiated.

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